How does CBD work?
Your body actually has areas that are made specifically for cannabinoids — they are called cannabinoid receptor sites, and cannabinoids bind to theses receptors on your cells. Certain receptors are heavily concentrated in the central nervous system while others are found in almost every organ of the body. Cannabinoid receptors are found in the skin, digestive tract, and even in the reproductive organs.
These sites make up the endocannabinoid system, which is responsible for numerous physiological and mental processes that occur naturally within the body.
These receptors fall into two types: CB1 and CB2. CB1 receptors are found mainly in the brain (but also in the liver, kidneys, and lungs), while CB2 receptors are found mainly in the immune system.
Also, since people often take numerous different cannabinoids together (for example, using medical marijuana), it is hard to attribute specific effects to specific cannabinoids. That’s because unprocessed cannabis includes more than 60 different types of cannabinoids, including CBD and THC.
In addition, some cannabinoids interact synergistically, producing unique effects that are not found when using them individually. For example, CBD inhibits THC’s psychotropic effects when the two are taken together. However, CBD does this (and produces many other effects) without directly interacting with the cannabinoid receptors. At first, scientists thought there was a third type of CBD receptor just for Cannabidiol, but the answer was far more interesting and revealing.
CBD is fairly unique as far as cannabinoids go, because it does not seem to interact directly with either the CB1 or CB2 receptors. So what does it do if it’s not interacting directly with our receptors?
Here’s where it gets good… Cannabidiol has a particularly low potential for binding with the CB1 and CB2 receptors, but instead acts as an antagonist of the receptors’ agonists. That’s a mouthful. In layman’s terms, this means that CBD keeps the receptors working at optimal capacity and helps the function of all other cannabinoids, including the body’s own endocannabinoids. The indirect interactions of CBD with the endocannabinoid system has many effects, some of which surprised scientists and are still being researched.
Some of CBD’s functions include:
✓ Effectively increases CB1 density, amplifying the effects of all cannabinoids that bind to CB1 receptors.
✓ Acts as a 5-HT1a receptor agonist in the brain. This means that CBD has calming and soothing effects such as some potent analgesics, but without the side effects.
✓ Acts as inverse agonist of CB2 receptors, effectively reducing the effects of cannabinoids that make CB2 receptors less responsive.
✓ Acts as an antagonist for the putative GPR55 receptor, an element of the endocannabinoid system that is still being researched. (It is suggested that GPR55 may be a third type of cannabinoid receptor altogether.)
Between the above functions, most of CBD’s observed effects are well explained. However, scientists are still unclear about how some effects of Cannabidiol are actually occurring. The most possible explanation is via the hypothetical GPR55 receptor, or through more indirect and synergistic effects that still await discovery.
The indirect nature of CBD’s effects have made it difficult for scientists to pinpoint its exact effects up to now, but many positive effects of this unusual phytocannabinoid are still being studied.
The endocannabinoid system is closely interconnected with the nervous and immune system. Since CBD has been shown to boost just about every function of our cannabinoid receptors, it is proven to have far-reaching soothing and relaxing effects.
The ECS as the greatest neurotransmitter system in the body. It lends a hand in seemingly just about everything, including:
•mood •memory •motor control •immune function •pain perception •appetite •sleep •reproduction •bone development
Four primary purposes of the ECS include neuroprotection, stress recovery, immune balance, and homeostatic regulation. The last one is a fancy way of referring to a system that creates optimum energy balance in the body.
Somehow, CBD seems to tap into this balancing system to produce its therapeutic effects. CBD is able to interact with cells in our bodies because the molecule has a similar composition to similar chemicals that the human body produces naturally, called endocannabinoids. It’s not often that a plant compound can make headlines over and over again. However, CBD is a phytocannabinoid with some serious life-saving potential.
Hemp vs Marijuana
What’s the Difference? There’s often some confusion between hemp CBD oil vs marijuana CBD oil. Both come from the cannabis sativa plant, but the biology of the two are decidedly different. While both plants contain compounds known as cannabinoids, marijuana contains the most well-known cannabinoid, THC (responsible for the “high” most people associate with cannabis in general) while hemp contains large amounts of CBD (also known as cannabidiol, which contains no psychoactive effects).
Industrial Hemp Supplements
Since hemp is naturally rich in CBD and has been bred to have only trace amounts of THC, many people today are turning to hemp products as an alternative to medical marijuana. Medical marijuana on the other hand, is not legal in all states in the US and many countries worldwide, while products made from hemp can be a safe and legal alternative. You can get many of the same beneficial effects of medical marijuana from hemp products without getting “high.”
When made into an oil (whether it’s hemp or marijuana oil), the compounds stay intact. And it’s the compounds contained in the plant that mark the only difference between marijuana and hemp at all. The single most distinguishing feature between marijuana and hemp oil is the amount of THC contained in each.
Marijuana oil generally contains 5-20% THC and has a higher ratio of THC than CBD. Hemp oil contains very little THC. For an oil to be considered hemp, it must contain less than 0.3% THC. Marijuana oil, on the other hand, contains higher doses of THC oil and causes the high most people associate with marijuana.
Interestingly enough, the high amounts of CBD contained in hemp oil have been shown to counteract the psychoactive effects of THC. For instance, if someone’s consumed “too much” high-THC marijuana oil, a hemp oil could reduce the effects.
Industrial hemp is produced by strains of Cannabis sativa that have been specifically bred to produce the lowest concentrations of THC possible and are instead selected and bred to grow taller and sturdier. Industrial hemp is exclusively made from Cannabis sativa.
Here’s the main concept to understand, Cannabidiol is still Cannabidiol in regard to its chemical composition, CBD remains unchanged regardless of which plant produces it.
However, the main question people have is not just about the CBD compound, which is constant from plant to plant, but the actual difference in CBD oil from various plants. Naturally occurring CBD is the same CBD regardless of the plant it came from, however, CBD and CBD oil are not in fact the same thing. As we’ve seen above, CBD is a chemical compound, while CBD oil is a mixture of various natural substances as they are derived from the plant of cannabis.
The production of hemp oil involves extracting the fatty acids from the stalks of the cannabis plant. Within these fatty acids fat-soluble substances can be found, and as cannabinoids are fat-soluble, they come out of the plant, dissolved in the oil.
Let’s use an example here. A high-CBD hemp oil product made from hemp. It has a concentration of CBD between 18% and 24%. This means that it has 18%–24% parts CBD dissolved in the actual oil, which is composed by other substances. So 18%–24% is pure CBD, and the rest are hemp oil extracts and other fatty acid substances.
The main point here is that CBD is always CBD, but CBD oil from hemp is not the same as the oil that is extracted from medical marijuana.
The main difference between the two remains that CBD oil from medical marijuana can contain any varying amount of THC. As a result, this type of CBD oil is considered a Schedule 1 drug and is not legal in many states in the US and countries worldwide.
Besides the difference in THC concentration, the CBD oils will also have differing amounts of other cannabinoids. But those make up a much smaller percentage of the overall volume and are not as pronounced in their effects as CBD or THC are. So, if you are looking for a safe and legal CBD oil product, our CBD oil produced from hemp is a great choice, because it’s naturally rich in CBD and has 0% THC.
Is Cannabidiol Legal?
What’s it’s Current Legal Status? This is a tricky question, because Cannabidiol comes in two main forms.
Cannabidiol can come from medical marijuana plants or from industrially grown hemp plants. Both are varieties of Cannabis, but they are grown for different purposes, and each one comes with its own legal status.
In addition to the above complication, you must also consider your country or state to figure out whether Cannabidiol is legal in your area. But first, let’s discuss the two types of Cannabidiol.
Cannabidiol from Medical Marijuana.
The first form of Cannabidiol is extracted from medical marijuana plants. These plants are grown to be high in CBD but have varying amounts of the psychoactive compound THC. They are sold to licensed dispensaries and prescribed by doctors for particular conditions in places where marijuana is regulated — like the US.
While medical marijuana is grown to be high in CBD for the treatment of specific ailments, the THC content can vary dramatically, sometimes getting as high as the CBD content.
The problem with medical marijuana (besides the possibility of getting a strain that is high in THC) is that it’s not currently legal everywhere. In the United States, you must be living in certain states and obtain a prescription from a doctor to receive medical marijuana.
Cannabidiol from Industrial Hemp Cannabidiol oil that comes from industrial hemp plants, like our products, are a different story. The FDA of the United States considers hemp oil (and it’s derivative CBD) to be a dietary supplement since they are made from industrial hemp plants.
If you live in the US, this means you don’t need a prescription and can legally purchase and consume Cannabidiol in any state.
Cannabidiol from industrial hemp also has the added benefit of having NO THC. This is why it’s not possible to get “high” with our products. There simply isn’t any THC.